Fournier’s gangrene (FG) is a rare and often severe necrotizing soft tissue infection of the perineum and genital region. A primary etiology can be identified in up to 95% of cases, including folliculitis, hidradenitis and perirectal/perianal abscess, invasive anorectal or urogenital procedures (i.e., Fournier's gangrene is a rare but serious and potentially life-threatening infection. patients taking SGLT2 inhibitors should be advised to seek urgent medical attention if they experience severe pain, tenderness, erythema, or swelling in the genital or perineal area accompanied by fever or malaise. urogenital infection or perineal The authors note that the cause of Fournier’s gangrene can be established in 95% of cases; the disease usually occurs because of infectious processes of the urogenital tract, anorectal area, or skin of the genitals. Fournier gangrene develops commonly in immunocompromised patients with diabetes, The symptoms of gangrene vary depending on the underlying cause. It can affect any part of the body, but typically starts in the toes, feet, fingers or hands. General symptoms of gangrene include: red, purple or black skin in the affected area, which may be harder to see on black or brown skin. swelling of the affected area
SGLT2 inhibitors and Fournier's gangrene – GPNotebook
Fournier's gangrene (FG) is named after Alfred Fournier who described it as a rapidly progressive necrotizing fasciitis of the perineum and external genital organs in young adults with unknown cause in [].The disease mostly affects men between 50 and 60 years of age and is considered uncommon in the Oct;57 (4) doi: /[HOST]ed Fournier gangrene (FG) is a rare, life-threatening infection that can result in significant morbidity and mortality, with many patients requiring emergency department (ED) management for complications and stabilization. This narrative review provides an evidence-based The exact cause of Fournier gangrene is not always clear, but several factors are believed to contribute to its development. Surgical intervention: Surgical procedures in the genital or perineal region can increase the risk of developing Fournier gangrene. This includes procedures such as surgery for What causes Fournier gangrene? Fournier gangrene typically occurs secondary to an infection of the genital area or other nearby organs, like the urinary tract or skin. Background. Fornier gangrene is an extremely rare disease of the genitals. This disease is a result of the urogenital tract, anorectal area, and genital skin infections, Background. Fournier’s gangrene (FG) is a devastating necrotising disease that affects the perineum and genitourinary regions. The common cause of FG is poly-microbial infections, where the diabetes mellitus is an attributing common risk factor (Shyam and Rapsang []).Study has shown that males, especially in Introduction and background. In the United States, Fournier’s gangrene (FG) is a rare and fatal form of necrotizing fasciitis, with an incidence rate of approximately per , males [].Even with aggressive treatment, the current mortality rate for FG is approximately 40% [], with literature estimates
Fournier’s Gangrene Diagnosis and Treatment: A Systematic Review
Fournier’s gangrene can occur in people who do not have diabetes, but is more common in people with diabetes. It is estimated to occur in approximately 1 in , patients This causes anesthesia of the overlying skin. In specific cases, normal commensals become virulent, aiding in further spreading of the infection. For example, in Fournier’s gangrene, Escherichia coli and Candida albicans have been isolated from the wound, together with lactobacilli, coliforms, Klebsiella, Fournier’s gangrene (FG) is a severe form of soft tissue infection that occurs in the perianal, perineal, and genital regions characterized by purulent necrosis caused by multiple types of anaerobic and aerobic microorganisms (Figs. 1 and 2). FG causes septic shock and multiple organ failure with mortality rates Further studies are required to determine whether it is in fact the SGLT-2 inhibitor itself that causes the gangrene, or if it is the subgroup of patients receiving this kind of anti-diabetic drug that constitutes the risk. 4. Conclusion. New oral anti-diabetic drugs, SGLT-2 inhibitors, may be associated with Fournier’s Background. Fournier gangrene was first identified in , when the French venereologist Jean Alfred Fournier described a series in which 5 previously healthy Fournier's Gangrene Causes. Fournier gangrene results from a bacterial infection in the genital area. Most cases are sparked by a combination of aerobic (requiring air) and